Publications
Richard Givens
Publications between 1997 – present:
(of 101 publications total).
78. C. Park and R. S. Givens, New Photoactivated Protecting Groups 6. p-Hydroxyphenacyl: A Phototrigger for Chemical and Biochemical Probes. J. Am. Chem. Soc., 119, 1997, 2453-2463.
79. Givens, R. S.; Jung, A.; Park, C-H.; Weber, J.; Bartlett, W.; New Photoactivated Protecting Groups. 7. p-Hydroxyphenacyl: p-Hydroxyphenacyl: A Phototrigger for Excitatory Amino Acids and Peptides, J. Am. Chem. Soc. 119, 1997, 8369-8370.
80. Givens, R. S.; Weber, J. J. F.; Jung, A. H.; Park, C.-H. New Photoprotecting Groups: Desyl and p-Hydroxyphenacyl Phosphate Carboxylate Esters in Methods in Enzymology on ACaged Compounds: Chemistry, Instrumentation, and Applications@, Gerard Marriott, ed., 1998, 291,1- 29 (invited).
81. Kandler, K., Givens, R.S. & Katz, L.C. Photostimulation with caged glutamate, in Imaging Neurons, Yuste, R., Lanni, F. & Konnerth, A. (eds.) (2000), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 27/1 –27/9.
82. Kuroda, N.; Hosoki, S.; Nakashima, K.; Akiyama, S.; Givens, R. S. Photographic Detection of Fluorescent-Labelled Oligodeoxynucleotide in the Blotting Format by Peroxyoxalate Chemiluminescence, J. Biolumin. Chemilumin., 1998, 13, 101-105.
83.
Rajesh, C. S.; Givens, R.; Wirz, J. Kinetics and Mechanism of
Phosphate Photorelease from Benzoin Diethyl Phosphate: Evidence for
Adiabatic Fission to an α-Keto Cation in the Triplet State, J. Am.
Chem. Soc., 2000, 122, 611-618.
(Full paper).
84. Givens, R. S.; Weber, J. F. W.; Conrad II, P. G.; Orosz, G.; Donahue, S. L.; Thayer, S. A New Phototriggers 9: p-Hydroxyphenacyl as a C-Terminus Photoremovable Protecting Group for Oligopeptides, J. Am. Chem. Soc. 2000, 122, 2687-2697 (Full paper).
85. Geibel,
S.; Barth, A.; Amslinger, S.; Jung, A.
H.; Burzik, Christiane; Clarke, Ronald J.; Givens, R.; Fendler, K. P3-[2-(4-hydroxyphenyl)-2-oxo]ethyl ATP for the rapid activation of the
Na+,K+-ATPase.
Biophys. J. 2000,
79(3), 1346-1357.
86. Conrad II, Peter G.; Givens, Richard S.; Weber, J. F. W.; Kandler, K. New Phototriggers 10: Extending the p,p* Absorption to Release Peptides in Biological Media, Org. Letts 2000, 2, 1545-1547.
87. Conrad II, P. G.; Givens, R. S.; Hellrung, B.; Rajesh, C. S., Ramseier, M.; Wirz, J. p-Hydroxyphenacyl Phototriggers: The reactive Excited State of Phosphate Photorelease, J. Am. Chem. Soc. 2000, 122, 9346-9347 (communication).
88. Zou, K.; Miller, T. W.; Givens, R. S.; Bayley, H. Caged Thiophphotyrosine Peptides, Angew. Chem. Int. Ed. 2001, 40, 3049-3051.
89. Chimilio, L. A.; Givens, R. S. Solvolytic Behavior and Photorearrangement of p-Hydroxyphenacyl Sulfonates: A Comparative Study, Org. Letts. (to be submitted).
90. Zou, K.; Cheley, S.; Givens, R. S.; Bayley, H. Catalytic subunit of protein kinase A caged at the activating phosphothreonine, J. Amer. Chem. Soc., 2002, 124, 8220-8229.
91. Timberlake, G. T.; Reddy, G. K.; Steno-Bittel, L.; Weber, J. J. W.; Amslinger, S.; Givens, R. S. Photoactivated coumaryl-diazopyruvate fluorescent label for amine functional groups of tissues containing type I collagen., Photochem. Photobiol., 2002, 76(5), 473-479.
92. Givens, R. S.; Lee, J.-I. The p-Hydroxyphenacyl Photoremovable Protecting Group, J. Photoscience, 2003, 10, 37 - 48.
93.
Givens, R. S.; Conrad, P. G. II; Yousef, A. L.; Lee, J.-I., Photoremovable
Protecting Groups in “CRC Handbook of Organic Photochemistry and
Photobiology, 2nd Edition” W. M. Horspool, ed. (2003),
Ch. 69, pp 69.1 – 69.46.
95. Zou, X; Archibald, S.J.; Hassan, A. M., Givens, R. S.; McCasland, A. K.; Busch, D. H. Toward the soil poultice and a new separation methodology: Rebinding of macrocycle metal complexes to molecularly imprinted polymers specifically templated via hydrogen bonding, 2003, in revision.
96. Sul, J-Y; Orosz, G.; Givens, R. S.; Haydon, P. G. Astrocytic Circuits in the Hippocampus, Neuron Glia Biology, 2004, 1, 3-10.
97. Hasan, M. M.; Zhang, C.; Lee, J.-I.; Bushan, K. M.; McCasland, A.; Givens, R. S.; Busch, D. H. Dynamics of switch-binding by a linear ligand that transforms to a macrocycle upon chelation to a metal ion: synthesis, kinetics, and equilibria, EMSP Symposium, ACS Meeting, New York, NY, 2003, 0000 (in press).
98. Givens, R. S.; Goeldner, M. (co-editors) “Dynamic Studies in Biology: Phototriggers, Photoswitches, and Caged Biomolecules” J. Wiley, and Sons February, 2005..
99. Givens, R. S.; Yousef, A. p-Hydroxyphenacyl: A Photoremovable Protecting Group for Caging Bioactive Substrates (Chp. Ic) in “Dynamic Studies in Biology: Phototriggers, Photoswitches, and Caged Biomolecules” J. Wiley, and Sons. (2005), pp. 55 – 75, in press.
100. Givens, R. S.; Lee, J.-I.; Kotala, M. Mechanistic overview of phototriggers and cage release (Chp. 2) in “Dynamic Studies in Biology: Phototriggers, Photoswitches, and Caged Biomolecules” J. Wiley, and Sons. (2005), pp. 95 –129, in press.
101. Zou, X.; Mosha, D.; Archibald, S.J.; McCasland, A.K.; Hassan, A. M.; Givens, R. S.; Busch, D. H. Toward the Soil Poultice and a New Separations Methodology: Rebinding of Macrocyclic Metal Complexes to Molecularly Imprinted Polymers Specifically Templated via Non-covalent Interactions, Journal of Coordination Chemistry (2004), vol, ppg’s.(in press).
102. Timberlake, G. T.; Yousef, A. L., Chiles, S. R.; Moses, R. A.; Givens, R. S. Bonding Corneal Tissue: Applications of photoactivated diazopyruoyl crosslinking agent, (2005) Photochem. Photobiol., submitted.
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Recent Patents: (from a total of 4)
4. Richard S. Givens, George T. Timberlake, Peter G. Conrad II, Photo-triggerable, Collagen Crosslinking Compounds for Wound Closure. Patent # 6,783,539 (US) August 31, 2004.
Photoswitching
Structure from : Chang, C. –Y.; Fernandez, T.; Panchal, R.;Bayley, H (1998) Caged Catalytic Subunit of Camp-dependent Protein Kinase, J. Am. Chem. Soc., 120, 7661-7662
● Richard S. Givens; Jong-Ill Lee; The p-Hydroxyphenacyl Photoremovable Protecting Group,
Journal of Photoscience 2002 (in press)
● Jong-Ill Lee, Richard S. Givens; The Photoactivation of Amino Acid and Peptide Side Chains: New Applications of the pHP Phototrigger, Presentation, 37th ACS Midwest Regional, October 23-25, 2002, Lawrence, KS
● Yousef, A. L.; Sahai, M.; Givens, R. S.; New Light Activated Caged Compounds : Extending the Utility of the p-hydroxyphenacyl Photoproducting group, Presentation, 37th ACS Midwest Regional, October 23-25, 2002, Lawrence, KS
●
Zou, K.; Cheley, S.; Givens, R. S.; Bayley, H. Catalytic subunit of
protein kinase A caged at the activating phosphothreonine, J. Amer.
Chem. Soc., 2002, 124, 8220-8229.
● Zou, K.; Miller, T. W.; Givens, R. S.; Bayley, H. Caged Thiophphotyrosine Peptides, Angew. Chem. Int. Ed. 2001, 40, 3049-3051.
●
Conrad II, P. G.; Givens, R. S.; Hellrung, B.; Rajesh, C. S.,
Ramseier, M.; Wirz, J. p-Hydroxyphenacyl Phototriggers: The
reactive Excited State of Phosphate Photorelease, J. Am. Chem. Soc.
2000, 122, 9346-9347.
●
Conrad II, Peter G.; Givens, Richard S.; Weber, J. F. W.; Kandler,
K. New Phototriggers 10:
Extending the p,p*
Absorption to Release Peptides in Biological Media, Org. Lett. 2000,
2, 1545-1547.
●
Geibel, S.; Barth, A.; Amslinger, S.; Jung, A.
H.; Burzik, Christiane; Clarke, Ronald J.; Givens, R.; Fendler, K. P3-[2-(4-hydroxyphenyl)-2-oxo]ethyl ATP for the
rapid activation of the Na+,K+-ATPase.
Biophys.
J. 2000,
79(3), 1346-1357.
●
Givens, R. S.; Weber, J. F.W.; Conrad II, P. G.; Orosz, G.;
Donahue, S. L.; Thayer, S. A New Phototriggers 9: p-Hydroxyphenacyl
as a C-Terminus Photoremovable Protecting Group for Oligopeptides, J.
Am. Chem. Soc. 2000, 122, 2687-2697.
● Rajesh, C. S.; Givens, R.; Wirz, J. Kinetics and Mechanism of Phosphate Photorelease from Benzoin Diethyl Phosphate: Evidence for Adiabatic Fission to an α-Keto Cation in the Triplet State, J. Am. Chem. Soc., 2000, 122, 611-618.
Photostitching
picture taken by Ricardo J. Aponte.
● Givens, R. S.; Timberlake, G. T.; Conrad, P. G. II; Yousef, A. L.; Weber, J. F. W.; Amslinger, S. Photoactivated Diazopyruvate Cross-linking Agent for Bonding Tissues Containing Type I Collagen (manuscript in preparation)
● Givens, R. S.; Timberlake, G. T.; Conrad, P. G. II; Weber, J. F. W.; Amslinger, S. A New Photoactivated Crosslinking Agent for Proteins: Applications to Tissue Welding of Type I Collagen, Photochem. Photobiol., 2002 (accepted, July, 2002)
● Yousef, A. L.; Aponte, R. J.; Timberlake, G. T.; Givens, R. S.; Tensile Strength of Photochemically Bonded Bovine Ligament Tissue Presentation, 37th ACS Midwest Regional, October 23-25, 2002, Lawrence, KS
● Yousef, A. L.; Timberlake, G. T.; Conrad, P. G.; Weber, J. F. W.; Amslinger, S.; Givens, R. S.; New Photoactivated Cross Linking Agents for Proteins: Applications to Tissue Welding of Type I Collagen, Poster, 224th ACS National Meeting, August 18-22, 2002, Boston, MA
New Separations Technology
Picture from : National Geographic Society, 2002.
http://maqma.nationalgeographic.com/ngm/0207/feature1/index.html
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